A novel in vivo test method for evaluating the infrared radiation protection provided by sunscreen products

  title={A novel in vivo test method for evaluating the infrared radiation protection provided by sunscreen products},
  author={Su Ji Kim and Jiyoun Bae and Sung Eun Lee and Jun Bae Lee and Chun Ho Park and Doo Hyeon Lim and Myeong Sam Park and Jaehyoun Ha},
  journal={Skin Research and Technology},
  pages={890 - 895}
Infrared radiation (IR) exposure generates reactive oxygen species and induces matrix metalloproteinase‐1 expression in human skin. Moreover, while not as acute as ultraviolet radiation, repeated infrared irradiation can result in the photoaging of skin. Broad‐spectrum sunscreens can protect skin from IR, but no human in vivo test methods for the evaluation of sunscreens' IR protection effect have been developed. We aimed to develop such a method. 
In vivo determination of the Infrared‐A protection factor on human skin
  • Su Ji Kim, H. Lee, Jun Bae Lee
  • Biology, Medicine
    Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging
  • 2021
Evaluation of the physiological changes taking place on the skin surface is insufficient for clinical investigations because daily or acute exposure to IR‐A rarely induces erythema or pigmentation.
Recent Trends of Sunscreen Cosmetic: An Update Review
Consumers should efficiently apply suitable products to improve sun protection, as well as to avoid the side effects of sunscreen.
Protective Effects of Titanium Dioxide-based Emulsion after Short-term and Long-term Infrared-A Ray Irradiation on Skin Cells
To accurately evaluate the protective effects of titanium dioxide-based emulsion from infrared-A rays (IRA) irradiation in daily life, we assessed the harmful effects of natural level of IRA


Development of an in vitro Test Procedure to Determine the Direct Infrared A Protection of Sunscreens and Non-Cosmetic Samples
In this study, the usability of a set-up consisting of a light source, an IRA-transmissible filter system and a sensor unit is proved, for the determination and quantification of the IRA protection of cosmetic and non-cosmetic samples.
Radical-Scavenging Activity of a Sunscreen Enriched by Antioxidants Providing Protection in the Whole Solar Spectral Range
Compared to the untreated skin, the sunscreen decreased the skin radical formation in the UV and VIS regions, and the possibility of the development of effective and safer sunscreen products is shown.
What is needed for a sunscreen to provide complete protection.
In an attempt to provide the necessary broad spectrum coverage, innovative research continues through the exploration of new compounds and novel combinations of chemical and physical UV filters with molecules that are capable of interfering with and/or preventing the deleterious effects of infrared A (IRA) radiation.
Radical Protection by Sunscreens in the Infrared Spectral Range
Four different, commercially available sunscreens and one COLIPA standard are investigated with regard to radical formation in the skin after IR irradiation, using electron paramagnetic resonance spectroscopy to investigate their influence on the radical protection of the skin.
Light - Instead of UV Protection: New Requirements for Skin Cancer Prevention.
Application of sunscreens and lotions protects against sunburn in the UV region of the solar spectrum and therefore is frequently used to extend people's stay in the sun, however, this behaviour can enhance the concentration of free radicals formed in the visible and infrared regions of theSolar spectrum, so that the critical radical threshold is exceeded and the skin may be damaged.
Infrared radiation-induced matrix metalloproteinase in human skin: implications for protection.
It is reported that incubation of cultured human dermal fibroblasts or treatment of human skin with specific antioxidants prevented IRA radiation-induced MMP-1 expression in vitro and in vivo, suggesting that IRA irradiation most likely promotes premature skin aging and topical application of appropriate antioxidants represents an effective photoprotective strategy.
Cutaneous effects of infrared radiation: from clinical observations to molecular response mechanisms
In response to IR irradiation, mitogen‐activated protein kinase signaling pathways were activated mediating the upregulation of matrix metalloproteinase‐1 expression and shows that IR radiation is capable of specifically interfering with cellular functions and provides a molecular basis for biological effects of IR on human skin.
Infrared radiation increases skin damage induced by other wavelengths in solar urticaria
Photodermatoses are typically investigated by analyzing the individual or combined effects of ultraviolet A (UVA), ultraviolet B (UVB), and visible light using light sources that simulate portions of
Free radicals induced by sunlight in different spectral regions – in vivo versus ex vivo study
Results indicate that radiation exposure in different spectral regions strongly influences radical production in skin and also results in changes in skin lipid composition, which is essential for barrier function.
Effects of infrared radiation and heat on human skin aging in vivo.
Sunlight damages human skin, resulting in a wrinkled appearance. Since natural sunlight is polychromatic, its ultimate effects on the human skin are the result of not only the action of each