A novel in vitro release method for submicron-sized dispersed systems

@article{Chidambaram1999ANI,
  title={A novel in vitro release method for submicron-sized dispersed systems},
  author={Nachiappan Chidambaram and Diane J. Burgess},
  journal={AAPS PharmSci},
  year={1999},
  volume={1},
  pages={32-40}
}
Sink conditions are often violated when using conventional release methods for dispersed systems. A novel reverse dialysis bag method was designed to overcome this problem. Model drug transport rates from submicron emulsions obtained using the conventional diffusion cell method and this novel method were compared. In the side-by-side diffusion cell method, emulsions were placed in the donor chamber and surfactant/buffer solutions in the receiver chamber. In the novel dialysis bag method… CONTINUE READING
BETA

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 41 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 21 REFERENCES

Injectable emulsions and suspensions

  • JB Boyett, CW Davis
  • 1989
1 Excerpt

Physicochemical characterization of polymeric nanocapsules and in vitro release evaluation of indomethacin as a drug model

  • N Armoury, H Fessi, JP Devissauget, F Puisieux, S. Benita
  • Sci Technol Pract Pharm
  • 1989
1 Excerpt

Theoretical evaluation of dispersed droplet radii in submicron oil-in-water emulsions

  • S Silvestri, RT Lostrito
  • Int J Pharm
  • 1989
1 Excerpt

A continuous flow system for in vitro evaluation of drug-loaded biodegradable colloidal barriers

  • F Koosha, RH Muller, SS. Davis
  • J Pharm Pharmacol. ;40:131P
  • 1988
1 Excerpt

Similar Papers

Loading similar papers…