A novel hybrid gene prediction method employing protein multiple sequence alignments

@article{Keller2011ANH,
  title={A novel hybrid gene prediction method employing protein multiple sequence alignments},
  author={Oliver Keller and Martin Kollmar and Mario Stanke and Stephan Waack},
  journal={Bioinformatics},
  year={2011},
  volume={27 6},
  pages={757-63}
}
MOTIVATION As improved DNA sequencing techniques have increased enormously the speed of producing new eukaryotic genome assemblies, the further development of automated gene prediction methods continues to be essential. While the classification of proteins into families is a task heavily relying on correct gene predictions, it can at the same time provide a source of additional information for the prediction, complementary to those presently used. RESULTS We extended the gene prediction… CONTINUE READING
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