A novel hepatitis B virus subgenotype D10 circulating in Ethiopia

@article{Hundie2017ANH,
  title={A novel hepatitis B virus subgenotype D10 circulating in Ethiopia},
  author={Gadissa Bedada Hundie and V Stalin Raj and D Gebre Michael and Suzan D. Pas and Marion P. G. Koopmans and Albert D.M.E. Osterhaus and Saskia L. Smits and Bart L. Haagmans},
  journal={Journal of Viral Hepatitis},
  year={2017},
  volume={24}
}
Hepatitis B virus (HBV) is genetically highly divergent and classified in ten genotypes and forty subgenotypes in distinct ethno‐geographic populations worldwide. Ethiopia is a country with high HBV prevalence; however, little is known about the genetic variability of HBV strains that circulate. Here, we characterize the complete genome of 29 HBV strains originating from five Ethiopian regions, by 454 deep sequencing and Sanger sequencing. Phylogenetically, ten strains were classified as… 
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Novel subgenotype D11 of hepatitis B virus in NaPo County, Guangxi, bordering Vietnam.
TLDR
The authors' data provide evidence for a novel subgenotype of HBV, provisionally designated HBV subgenotypes D1-D10, which is found to form a cluster in 23 genotype D isolates, branching out from other subgenotyp D sequences and supported by a 100 % bootstrap value.
Genetic diversity of hepatitis B virus in Yunnan, China: identification of novel subgenotype C17, an intergenotypic B/I recombinant, and B/C recombinants.
TLDR
Multiple subgenotypes - namely B1, B2, B4, C1, C2, C3, C4,C8 and C17 - and two distinct intergenotypic recombinants exist in Yunnan, China, highlighting the complex and diverse distribution pattern of HBV genotypic profiles.
A systematic genotype and subgenotype re-ranking of hepatitis B virus under a novel classification standard
Complete genome sequence of a hepatitis B virus isolate of genotype D2, subtype adrq+, from Brazil
TLDR
This isolate had a genome length of 3,062 nucleotides (nt), and no recombination events were observed in the BR32 genome that could explain the occurrence of the subtype adr in a genotype D isolate.
Characteristics and evolutionary history of hepatitis B virus quasi-subgenotype B3 in Southeast Asia.
Genetic diversity of hepatitis C virus in Ethiopia
TLDR
Investigation of the distribution and genetic diversity of HCV genotypes/subtypes in Ethiopia found genotype 4 HCV viruses, subtypes 4d and 4r, are most prevalent in Ethiopia, considered to be difficult to treat.
Hepatitis B virus genotypes A1, A2 and E in Cape Verde: Unequal distribution through the islands and association with human flows
TLDR
Interestingly, the HBV/A1 isolates from São Vicente were closely related to Brazilian sequences into the Asian-American clade, which suggests the dissemination of common African ancestors through slave trade.
Reconstruction of the spatial and temporal dynamics of hepatitis B virus genotype D in the Americas
TLDR
The detailed evolutionary history of HBV/D in the Americas was investigated by using different evolutionary time scales, and suggested times of the most recent common ancestor for the American HBv/D subgenotypes coincident with mass migratory movements to Americas during the 19th and 20th centuries.
Molecular evolution and phylodynamics of hepatitis B virus infection circulating in Iran
TLDR
Phylodynamic inference clearly demonstrates a unique homogenous pattern of HBV genotype D compatible with a steady configuration of the decreased effective number of infections in the population in recent years, possibly due to the implementation of blood donation screening and vaccination programs.
Molecular epidemiology of hepatitis B virus among HIV co-infected and mono-infected cohorts in Northwest Ethiopia
TLDR
The observed virological characteristics could contribute for evidence-based management of viral hepatitis in Ethiopia where antiretroviral therapy guidelines do not cater for viral hepatitis screening during HIV co-infection.
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