A novel hemostatic delivery device for thrombin: biodegradable poly(D,L-lactide-co-glycolide) 50:50 microspheres.

@article{Smeets2011ANH,
  title={A novel hemostatic delivery device for thrombin: biodegradable poly(D,L-lactide-co-glycolide) 50:50 microspheres.},
  author={Ralf Smeets and Frank Gerhards and Jamal M. Stein and Rui Miguel Pereira Paz and Stephan Vogt and Christoph Pautke and Jochen Weitz and A. van der Kolk},
  journal={Journal of biomedical materials research. Part A},
  year={2011},
  volume={96 1},
  pages={177-85}
}
Topical thrombins are locally active hemostatic agents that can be used to minimize blood loss during any surgery. The aim of this study was to design and investigate a thrombin-containing biodegradable hemostyptic device with an optimized drug release profile to promote local blood clot formation. It is effective with ongoing systemic antithrombotic… CONTINUE READING