A novel gnd mutation leading to increased L-lysine production in Corynebacterium glutamicum.

@article{Ohnishi2005ANG,
  title={A novel gnd mutation leading to increased L-lysine production in Corynebacterium glutamicum.},
  author={Junko Ohnishi and Ritsuko Katahira and Satoshi Mitsuhashi and Shingo Kakita and Masato Ikeda},
  journal={FEMS microbiology letters},
  year={2005},
  volume={242 2},
  pages={
          265-74
        }
}
  • Junko Ohnishi, Ritsuko Katahira, +2 authors Masato Ikeda
  • Published in FEMS microbiology letters 2005
  • Medicine, Biology
  • Toward more efficient L-lysine production, we have been challenging genome-based strain breeding by the approach of assembling only relevant mutations in a single wild-type background. Following the creation of a new L-lysine producer Corynebacterium glutamicum AHP-3 that carried three useful mutations (lysC311, hom59, and pyc458) on the relevant downstream pathways, we shifted our target to the pentose phosphate pathway. Comparative genomic analysis for the pathway between a classically… CONTINUE READING

    Create an AI-powered research feed to stay up to date with new papers like this posted to ArXiv

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 67 CITATIONS, ESTIMATED 59% COVERAGE

    Amino Acid Fermentation

    VIEW 4 EXCERPTS
    CITES BACKGROUND
    HIGHLY INFLUENCED

    Lysine Fermentation: History and Genome Breeding.

    • Masato Ikeda
    • Medicine, Biology
    • Advances in biochemical engineering/biotechnology
    • 2016
    VIEW 5 EXCERPTS
    CITES BACKGROUND

    Metabolic flux distributions: genetic information, computational predictions, and experimental validation

    VIEW 6 EXCERPTS
    CITES BACKGROUND
    HIGHLY INFLUENCED

    [Twenty years development of metabolic engineering--a review].

    • Xueli Zhang
    • Biology, Medicine
    • Sheng wu gong cheng xue bao = Chinese journal of biotechnology
    • 2009
    VIEW 2 EXCERPTS
    HIGHLY INFLUENCED

    FILTER CITATIONS BY YEAR

    2005
    2019

    CITATION STATISTICS

    • 7 Highly Influenced Citations