A novel glutaminase isoform in mammalian tissues.

Abstract

The synthesis of neurotransmitter glutamate in brain is mainly carried out by glutaminase enzymes. This synthesis must be exquisitely regulated because of its harmful potential giving rise to excitotoxic damage. It is noteworthy that two glutaminase isozymes coded by different genes are expressed in the brain of mammals. The need for two genes and two… (More)
DOI: 10.1016/j.neuint.2009.02.021

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