A novel germ line-specific gene of the phosducin-like protein (PhLP) family. A meiotic function conserved from yeast to mice.

@article{Lopez2003ANG,
  title={A novel germ line-specific gene of the phosducin-like protein (PhLP) family. A meiotic function conserved from yeast to mice.},
  author={Pascal Jean Lopez and Ruken Yaman and Luis Andr{\'e}s L{\'o}pez-Fern{\'a}ndez and Fr{\'e}d{\'e}rique Vidal and Daniel Puel and Philippe Clertant and François Cuzin and Minoo Rassoulzadegan},
  journal={The Journal of biological chemistry},
  year={2003},
  volume={278 3},
  pages={1751-7}
}
We identified a new member of the phosducin-like (PhLP) protein family that is predominantly, if not exclusively, expressed in male and female germ cells. In situ analysis on testis sections and analysis of purified spermatogenic cell fractions evidenced a stage-specific expression with high levels of RNA and protein in pachytene spermatocytes and round spermatids. Three mRNA species were detected, which correspond to different polyadenylation sites and vary in abundance during germ cell… CONTINUE READING