A novel genomics approach for the identification of drug targets in pathogens, with special reference to Pseudomonas aeruginosa

@article{Sakharkar2004ANG,
  title={A novel genomics approach for the identification of drug targets in pathogens, with special reference to Pseudomonas aeruginosa},
  author={Kishore R. Sakharkar and Meena Kishore Sakharkar and Vincent T. K. Chow},
  journal={In silico biology},
  year={2004},
  volume={4 3},
  pages={355-60}
}
Complete genome sequences of several pathogenic bacteria have been determined, and many more such projects are currently under way. While these data potentially contain all the determinants of host-pathogen interactions and possible drug targets, computational tools for selecting suitable candidates for further experimental analyses are currently limited. Detection of bacterial genes that are non-homologous to human genes, and are essential for the survival of the pathogen represents a… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 72 extracted citations

Similar Papers

Loading similar papers…