A novel gene signature based on five glioblastoma stem-like cell relevant genes predicts the survival of primary glioblastoma

@article{Chai2017ANG,
  title={A novel gene signature based on five glioblastoma stem-like cell relevant genes predicts the survival of primary glioblastoma},
  author={Ruichao Chai and Kenan Zhang and Kuanyu Wang and Guanzhang Li and Ruoyu Huang and Zheng Zhao and Yanwei Liu and Jing Chen},
  journal={Journal of Cancer Research and Clinical Oncology},
  year={2017},
  volume={144},
  pages={439-447}
}
PurposePrimary glioblastoma (pGBM) is the most common and lethal type of neoplasms in the central nervous system, while the existing biomarkers, lacking consideration on the stemness changes of GBM cells, are not specific enough to predict the complex prognosis respectively. We aimed to build a high-efficiency prediction gene signature related to GBM cell stemness and investigate its prognostic value in primary glioblastoma.MethodsDifferentially expressed genes were screened in GSE23806… CONTINUE READING
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