A novel gene (retinovin) expressed selectively in the early stage of chick retinal development.

@article{Itami2000ANG,
  title={A novel gene (retinovin) expressed selectively in the early stage of chick retinal development.},
  author={Masako Itami and Toshihiko Matsuo and Hiroshi Ohtsuki},
  journal={Biochemical and biophysical research communications},
  year={2000},
  volume={276 1},
  pages={
          12-5
        }
}
To understand molecular mechanisms of retinal development, genes expressed selectively only in the early stage of retinal development were isolated by subtractive hybridization based on suppression polymerase chain reaction. The retina has no layered structure in 7-day chick embryos, in contrast with the fully developed multilayered structure of neurons in 15-day embryos. The subtraction between cDNA derived from retinal tissues at these different stages, followed by repeat rounds of 5'-RACE… 
1 Citations
USPL1, a novel SUMO isopeptidase
TLDR
The goal of this work was to identify and perform initial characterization of a novel SUMO specific isopeptidase, and the identification of USPL1 (Ubiquitin Specific Protease Like 1) as a protein that reacts with SUMO-VME.

References

SHOWING 1-7 OF 7 REFERENCES
Identification and characterization of transcripts present at elevated levels in the undifferentiated chick retina.
  • R. Godbout
  • Biology, Medicine
    Experimental eye research
  • 1993
TLDR
The elevated levels of these five RNAs in the undifferentiated retina and the subsequent decrease in transcript levels observed upon tissue maturation indicate that the encoded proteins may play important roles in early retinal development.
Multipotential stem cells and progenitors in the vertebrate retina.
TLDR
While there is currently no evidence for a neural/glial stem cell in the adult mammalian retina, the retina of the mature mammal does not show regenerative capacity after damage, there is a possibility for the reinitiation of stem cell potential at the peripheral retinal margin, from the RPE or from the Müller glial cells.
Plasticity and differentiation of retinal precursor cells.
  • R. Adler
  • Biology, Medicine
    International review of cytology
  • 1993
TLDR
This chapter describes plasticity and differentiation of retinal precursor cells in culture, which shows their capacity to develop and maintain, even when grown in the absence of intercellular contacts, a highly elongated, compartmentalized, and polarized pattern of organization.
The effects of growth factors on multicellular spheroids formed by chick embryonic retinal cells.
TLDR
Multicellular spheroids formed in a dish for suspension culture would provide a convenient in vitro system to examine differentiation and transdifferentiation of the retina.
Continuous observation of multipotential retinal progenitor cells in clonal density culture.
TLDR
It is shown that even when cultured at clonal density in a homogeneous general environment, the retinal progenitor cells vary in proliferative capacity, cell cycle time, and in the cell types that they generate.
A novel gene (oculomedin) induced by mechanical stretching in human trabecular cells of the eye.
To understand molecular mechanisms underlying the response to pressure in human trabecular cells of the eye, genes induced by cyclic mechanical stretching were isolated by subtractive hybridization
Suppression subtractive hybridization: a method for generating differentially regulated or tissue-specific cDNA probes and libraries.
  • L. Diatchenko, Y. Lau, +8 authors P. Siebert
  • Biology, Medicine
    Proceedings of the National Academy of Sciences of the United States of America
  • 1996
TLDR
The results suggest that the SSH technique is applicable to many molecular genetic and positional cloning studies for the identification of disease, developmental, tissue-specific, or other differentially expressed genes.