A novel fusion of TPR and ALK in lung adenocarcinoma.

  title={A novel fusion of TPR and ALK in lung adenocarcinoma.},
  author={Yoon-La Choi and Maruja E. Lira and Mineui Hong and Ryong Nam Kim and So-Jung Choi and Ji-young Song and Kinnari Pandy and Derrick L. Mann and Joshua A. Stahl and Heather E. Peckham and Zongli Zheng and Joungho Han and Mao Mao and Jhingook Kim},
  journal={Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer},
  volume={9 4},
INTRODUCTION Anaplastic lymphoma kinase (ALK) fusion is the most common mechanism for overexpression and activation in non-small-cell lung carcinoma. Several fusion partners of ALK have been reported, including echinoderm microtubule-associated protein-like 4, TRK-fused gene, kinesin family member 5B, kinesin light chain 1 (KLC1), protein tyrosine phosphatase and nonreceptor type 3, and huntingtin interacting protein 1 (HIP1). METHODS AND RESULTS A 60-year-old Korean man had a lung mass which… CONTINUE READING
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