A novel function of insulin in rat dermis.

  title={A novel function of insulin in rat dermis.},
  author={Torbj\orn Nedreb\o and Tine Veronica Karlsen and Gerd S Salvesen and Rolf K. Reed},
  journal={The Journal of physiology},
  volume={559 Pt 2},
In this study we present a novel function of insulin in rat dermis. We investigated local effects of insulin on interstitial fluid pressure (Pif), and capillary albumin leakage and pro-inflammatory cytokine production in skin and serum after intravenous lipopolysaccharide (LPS), tumour necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta) challenge treated with a glucose-insulin-potassium regimen (GIK). The main objective for this study was to investigate anti-inflammatory effects… CONTINUE READING


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