A novel function of eIF2alpha kinases as inducers of the phosphoinositide-3 kinase signaling pathway.

Abstract

Phosphoinositide-3 kinase (PI3K) plays an important role in signal transduction in response to a wide range of cellular stimuli involved in cellular processes that promote cell proliferation and survival. Phosphorylation of the alpha subunit of the eukaryotic translation initiation factor eIF2 at Ser51 takes place in response to various types of… (More)

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@article{Kazemi2007ANF, title={A novel function of eIF2alpha kinases as inducers of the phosphoinositide-3 kinase signaling pathway.}, author={Shirin Kazemi and Zineb Mounir and Dionissios Baltzis and Jennifer F. Raven and Shuo Wang and J Krishnamoorthy and Olivier Pluquet and Jerry Pelletier and Antonis E. Koromilas}, journal={Molecular biology of the cell}, year={2007}, volume={18 9}, pages={3635-44} }