A novel function for the presenilin family member spe-4: inhibition of spermatid activation in Caenorhabditis elegans.

@article{Gosney2007ANF,
  title={A novel function for the presenilin family member spe-4: inhibition of spermatid activation in Caenorhabditis elegans.},
  author={Ryoko Gosney and W R Liau and Craig W Lamunyon},
  journal={BMC Developmental Biology},
  year={2007},
  volume={8},
  pages={44 - 44}
}
Sperm cells must regulate the timing and location of activation to maximize the likelihood of fertilization. Sperm from most species, including the nematode Caenorhabditis elegans, activate upon encountering an external signal. Activation for C. elegans sperm occurs as spermatids undergo spermiogenesis, a profound cellular reorganization that produces a pseudopod. Spermiogenesis is initiated by an activation signal that is transduced through a series of gene products. It is now clear that an… CONTINUE READING