A novel function for Hog1 stress-activated protein kinase in controlling white-opaque switching and mating in Candida albicans.

@article{Liang2014ANF,
  title={A novel function for Hog1 stress-activated protein kinase in controlling white-opaque switching and mating in Candida albicans.},
  author={Shen-Huan Liang and Jen-Hua Cheng and Fu-Sheng Deng and Pei-An Tsai and Ching-Hsuan Lin},
  journal={Eukaryotic cell},
  year={2014},
  volume={13 12},
  pages={1557-66}
}
Candida albicans is a commensal in heathy people but has the potential to become an opportunistic pathogen and is responsible for half of all clinical infections in immunocompromised patients. Central to understanding C. albicans behavior is the white-opaque phenotypic switch, in which cells can undergo an epigenetic transition between the white state and the opaque state. The phenotypic switch regulates multiple properties, including biofilm formation, virulence, mating, and fungus-host… CONTINUE READING
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