A novel fibrinolytic enzyme (nattokinase) in the vegetable cheese Natto; a typical and popular soybean food in the Japanese diet

@article{Sumi1987ANF,
  title={A novel fibrinolytic enzyme (nattokinase) in the vegetable cheese Natto; a typical and popular soybean food in the Japanese diet},
  author={Hiroyuki Sumi and Hiroki Hamada and Hiromi Tsushima and Hitoshi Mihara and Hisato Muraki},
  journal={Experientia},
  year={1987},
  volume={43},
  pages={1110-1111}
}
A strong fibrinolytic activity was demonstrated in the vegetable cheese Natto, which is a typical soybean food eaten in Japan. The average activity was calculated at about 40 CU (plasmin units)/g wet weight. This novel fibrinolytic enzyme, named nattokinase, was easily extracted with saline. The mol. wt and pI were about 20,000 and 8.6, respectively. Nattokinase not only digested fibrin but also the plasmin substrate H-D-Val-Leu-Lys-pNA (S-2251), which was more sensitive to the enzyme than… CONTINUE READING
Highly Influential
This paper has highly influenced 14 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
Highly Cited
This paper has 323 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 122 extracted citations

Secretory expression of a heterologous nattokinase in Lactococcus lactis

Applied Microbiology and Biotechnology • 2006
View 4 Excerpts
Highly Influenced

Activity assessment of microbial fibrinolytic enzymes

Applied Microbiology and Biotechnology • 2013
View 4 Excerpts
Highly Influenced

323 Citations

02040'98'03'09'15
Citations per Year
Semantic Scholar estimates that this publication has 323 citations based on the available data.

See our FAQ for additional information.