A novel family of retrotransposon-like elements in Xenopus laevis with a transcript inducible by two growth factors.

@article{Greene1993ANF,
  title={A novel family of retrotransposon-like elements in Xenopus laevis with a transcript inducible by two growth factors.},
  author={J. M. Greene and Hiroki Otani and Peter J. Good and Igor B Dawid},
  journal={Nucleic acids research},
  year={1993},
  volume={21 10},
  pages={2375-81}
}
A cDNA clone named 1A11 was isolated in a screen for genes that are activated by both mesoderm inducing factors FGF and activin in animal explants of Xenopus laevis embryos. In undisturbed embryos, 1A11 is expressed during the gastrula stage in the entire marginal zone where mesoderm originates, and later in the somites, the tailbud, and at much lower levels in lateral mesoderm. The 1A11 sequence of 4.5 Kb has a 220 bp repeat at its ends, indicative of a retrotransposon-like structure. A long… CONTINUE READING
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