A novel factor controlling bistability in Bacillus subtilis: the YmdB protein affects flagellin expression and biofilm formation.

@article{Diethmaier2011ANF,
  title={A novel factor controlling bistability in Bacillus subtilis: the YmdB protein affects flagellin expression and biofilm formation.},
  author={Christine Diethmaier and Nico Pietack and Katrin Gunka and Christoph Wrede and Martin Lehnik-Habrink and Christina Herzberg and Sebastian V. Huebner and J{\"o}rg St{\"u}lke},
  journal={Journal of bacteriology},
  year={2011},
  volume={193 21},
  pages={
          5997-6007
        }
}
Cells of Bacillus subtilis can either be motile or sessile, depending on the expression of mutually exclusive sets of genes that are required for flagellum or biofilm formation, respectively. Both activities are coordinated by the master regulator SinR. We have analyzed the role of the previously uncharacterized ymdB gene for bistable gene expression in B. subtilis. We observed a strong overexpression of the hag gene encoding flagellin and of other genes of the σ(D)-dependent motility regulon… CONTINUE READING
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