A novel dual-responsive core-crosslinked magnetic-gold nanogel for triggered drug release.

@article{Ghorbani2016AND,
  title={A novel dual-responsive core-crosslinked magnetic-gold nanogel for triggered drug release.},
  author={Marjan Ghorbani and Hamed Hamishehkar and Nasser Arsalani and Ali Akbar Entezami},
  journal={Materials science & engineering. C, Materials for biological applications},
  year={2016},
  volume={68},
  pages={436-444}
}
A facial approach was reported to prepare a novel dual-responsive core-crosslinked nanogel and investigated for the triggered methotrexate (MTX) release. Nanogels with core-shell architecture were synthesized by decoration of Au/Fe3O4 core/shell NPs using poly(ethylene glycol)-b-poly((N,N-dimethylamino)ethyl methacrylate-co-2-hydroxyethyl methacrylate)-maleic acid (PEG-b-P(DMAEMA-co-HEMA)-MA) for crosslinking and autoreduction processes. The second block containing amino groups and maleate… CONTINUE READING