A novel-designed Escherichia coli for the production of various polyhydroxyalkanoates from inexpensive substrate mixture

@article{Li2007ANE,
  title={A novel-designed Escherichia coli for the production of various polyhydroxyalkanoates from inexpensive substrate mixture},
  author={Rui Li and Quan Chen and Peng George Wang and Qingsheng Qi},
  journal={Applied Microbiology and Biotechnology},
  year={2007},
  volume={75},
  pages={1103-1109}
}
To efficiently produce polyhydroxyalkanoates (PHAs) from substrate mixture containing various carbon sources, Escherichia coli phosphotransferase system (PTS) mutants were constructed, in which the carbon catabolite repression in the presence of glucose was released. When cultivated in the medium containing glucose and xylose, E. coli LR1010, harboring phaC Re and phaAB Re genes from Ralstronia eutropha, could simultaneously consume glucose and xylose and accumulate short-chain-length PHA… CONTINUE READING
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Metabolic engineering and pathway construction for biotechnical production of relavent polyhydroxyalkanotes in microoganisms

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