A novel cyclosporine a drug-delivery system for prevention of human corneal rejection after high-risk keratoplasty: a clinical study.

@article{Shi2013ANC,
  title={A novel cyclosporine a drug-delivery system for prevention of human corneal rejection after high-risk keratoplasty: a clinical study.},
  author={Weiyun Shi and Min Chen and Lixin Xie and Mingna Liu and Hua Gao and Ting Wang and Xiang-gen Wu and Jing Zhao},
  journal={Ophthalmology},
  year={2013},
  volume={120 4},
  pages={695-702}
}
PURPOSE To evaluate the efficacy of a novel cyclosporine A (CsA) drug-delivery system (DDS) in the anterior chamber for suppressing the occurrence of rejection and improving the survival of corneal allografts after high-risk keratoplasty. DESIGN Single-center, noncomparative case series. PARTICIPANTS Ninety-two eyes of 92 patients with corneal blindness who required corneal transplantation at Shandong Eye Institute from May 2003 to June 2011. METHODS The CsA DDS was implanted into the… CONTINUE READING