A novel copper-catalyzed reductive coupling of N-tosylhydrazones with H-phosphorus oxides.

Abstract

We report here a novel C(sp(3))-P bonds formation via copper-catalyzed reductive coupling of N-tosylhydrazones with H-phosphorus oxides. A variety of aliphatic and aromatic substrates bearing electron-rich and electron-deficient substituents affords phosphine oxide derivatives with moderate to good yields. This work suggests a new transformation of aldehydes/ketones via N-tosylhydrazones to organophosphorus compounds.

Cite this paper

@article{Wu2012ANC, title={A novel copper-catalyzed reductive coupling of N-tosylhydrazones with H-phosphorus oxides.}, author={Lei Wu and Xio Zhang and Qing-Qing Chen and A Zhou}, journal={Organic & biomolecular chemistry}, year={2012}, volume={10 39}, pages={7859-62} }