A novel composite formulation of palmitoylethanolamide and quercetin decreases inflammation and relieves pain in inflammatory and osteoarthritic pain models

@inproceedings{Britti2017ANC,
  title={A novel composite formulation of palmitoylethanolamide and quercetin decreases inflammation and relieves pain in inflammatory and osteoarthritic pain models},
  author={Domenico Britti and R. Crupi and Daniela Impellizzeri and Enrico Gugliandolo and Roberta Fusco and Carlo Schievano and Valeria Maria Morittu and Maurizio Evangelista and R Di Paola and Salvatore Cuzzocrea},
  booktitle={BMC veterinary research},
  year={2017}
}
BackgroundOsteoarthritis (OA) is a common progressive joint disease in dogs and cats. The goal of OA treatment is to reduce inflammation, minimize pain, and maintain joint function. Currently, non-steroidal anti-inflammatory drugs (e.g., meloxicam) are the cornerstone of treatment for OA pain, but side effects with long-term use pose important challenges to veterinary practitioners when dealing with OA pain. Palmitoylethanolamide (PEA) is a naturally-occurring fatty acid amide, locally produced… CONTINUE READING
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