A novel combination of mild electrical stimulation and hyperthermia: general concepts and applications.

Abstract

This review discusses the basic concepts, effects and applications of hyperthermia and mild electrical stimulation (MES) using low-intensity direct current. It also proposes a novel combinatorial use of MES and hyperthermia, and briefly outlines the rationale and the effects of MES and hyperthermia combination treatment on certain diseases (diabetes, hepatic ischaemia/reperfusion injury and gastric ulcer). The integrated modalities of MES and hyperthermia might find therapeutic applications to stress-induced diseases and intractable diseases of dysregulated signalling pathways.

DOI: 10.3109/02656730903039605

Cite this paper

@article{Kai2009ANC, title={A novel combination of mild electrical stimulation and hyperthermia: general concepts and applications.}, author={Hirofumi Kai and Mary Ann Suico and Saori Morino and Tatsuya Kondo and Mariko Oba and Mikiko Noguchi and Tsuyoshi Shuto and Eiichi Araki}, journal={International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group}, year={2009}, volume={25 8}, pages={655-60} }