A novel cardiotropic murine adenovirus representing a distinct species of mastadenoviruses.

  title={A novel cardiotropic murine adenovirus representing a distinct species of mastadenoviruses.},
  author={Boris Klempa and Detlev H. Kr{\"u}ger and Brita Auste and Michal Stanko and Adalbert Krawczyk and Katrin F Nickel and Klaus Uberla and Alexander Stang},
  journal={Journal of virology},
  volume={83 11},
During cell culture isolation experiments to recover Dobrava hantavirus from a suspension of liver from a striped field mouse (Apodemus agrarius), an unknown virus was coisolated. Atypically for hantaviruses, it had extensive cytopathic effects. Using a random PCR approach, it was identified as a novel murine adenovirus, MAdV-3 (for MAdV type 3). A plaque-purified virus clone was prepared and further characterized. The complete genome sequence of MAdV-3 was determined to be 30,570 bp in length… CONTINUE READING
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