Corpus ID: 36204445

A novel bronchodilator xanthine apparently without adenosine receptor antagonism and tremorogenic effect.

@article{Lunell1983ANB,
  title={A novel bronchodilator xanthine apparently without adenosine receptor antagonism and tremorogenic effect.},
  author={E. Lunell and N. Svedmyr and K. Andersson and C. Persson},
  journal={European journal of respiratory diseases},
  year={1983},
  volume={64 5},
  pages={
          333-9
        }
}
  • E. Lunell, N. Svedmyr, +1 author C. Persson
  • Published 1983
  • Medicine
  • European journal of respiratory diseases
  • Enprofylline is a potent bronchodilating xanthine derivative that has been shown to have little or no ability to antagonize adenosine in a variety of cell types. In eight patients with chronic obstructive lung disease, a single dose of enprofylline (3.5 mg/kg) was given orally. A double blind, randomized, crossover comparison was made with oral theophylline (9.5 mg/kg) which is a potent and general adenosine receptor antagonist. Forced expiratory volume (FEV1), vital capacity, tremor of hands… CONTINUE READING
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