A novel bifunctional histone protein in Streptomyces: a candidate for structural coupling between DNA conformation and transcription during development and stress?

@inproceedings{Aldridge2013ANB,
  title={A novel bifunctional histone protein in Streptomyces: a candidate for structural coupling between DNA conformation and transcription during development and stress?},
  author={Matthew Aldridge and Paul D. Facey and Lewis W Francis and S. L. Bayliss and Ricardo del Sol and Paul Dyson},
  booktitle={Nucleic acids research},
  year={2013}
}
Antibiotic-producing Streptomyces are complex bacteria that remodel global transcription patterns and their nucleoids during development. Here, we describe a novel developmentally regulated nucleoid-associated protein, DdbA, of the genus that consists of an N-terminal DNA-binding histone H1-like domain and a C-terminal DksA-like domain that can potentially… CONTINUE READING