A novel bacteriocin from Enterococcus faecalis 478 exhibits a potent activity against vancomycin-resistant enterococci

@article{Phumisantiphong2017ANB,
  title={A novel bacteriocin from Enterococcus faecalis 478 exhibits a potent activity against vancomycin-resistant enterococci},
  author={Uraporn Phumisantiphong and Kanokrat Siripanichgon and Onrapak Reamtong and Pornphan Diraphat},
  journal={PLoS ONE},
  year={2017},
  volume={12}
}
The emergence of multidrug-resistant enterococci (MDRE) and particularly vancomycin-resistant enterococci (VRE) is considered a serious health problem worldwide, causing the need for new antimicrobials. The aim of this study was to discover and characterize bacteriocin against clinical isolates of MDRE and VRE. Over 10,000 bacterial isolates from water, environment and clinical samples were screened. E. faecalis strain 478 isolated from human feces produced the highest antibacterial activity… 
Antimicrobial Activity of a Bacteriocin Produced by Enterococcus faecalis KT11 against Some Pathogens and Antibiotic-Resistant Bacteria
TLDR
The results showed that bacteriocin KT11 was antagonistically effective against various Gram-positive and Gram-negative test bacteria, including vancomycin- and/or methicillin-resistant bacteria, as well as in combination with conventional antibiotics.
Anticancer and antimicrobial potential of enterocin 12a from Enterococcus faecium
TLDR
Enterocin 12a is a novel bacteriocin that has anticancer properties against human cell lines and negligible activity towards non-malignant cells and should be further evaluated for its anticancer potential in animal models.
Anti-Proliferative and Anti-Biofilm Potentials of Bacteriocins Produced by Non-Pathogenic Enterococcus sp.
TLDR
The multifunctional capabilities of the microbial-derived proteins identified in this study suggest potentially important roles as alternative treatments for biofilm-associated infections and cancer.
Antimicrobial activity of bacteriocins produced by Enterococcus isolates recovered from Egyptian homemade dairy products against some foodborne pathogens.
The increasing mandate for fresh-like food products and the possible hazards of chemically preserved foods necessitate the search for alternatives. Bacteriocins represent a promising food
Purification and characterization of bacteriocins active against Mycobacterium tuberculosis from lactic acid bacteria
TLDR
The results showed that BLIB04 effectively inhibited M. tuberculosis H37Rv, SHRE sensitive and HR resistant M tuberculosis.
Enterococcus spp. as a Producer and Target of Bacteriocins: A Double-Edged Sword in the Antimicrobial Resistance Crisis Context
TLDR
The purpose of this review is to present a current standpoint about the dual role of Enterococcus spp.
The Genus Enterococcus: Between Probiotic Potential and Safety Concerns—An Update
A considerable number of strains belonging to different species of Enterococcus are highly competitive due to their resistance to wide range of pH and temperature. Their competitiveness is also owed
...
1
2
3
...

References

SHOWING 1-10 OF 94 REFERENCES
Bacteriocins Produced by L. Fermentum and L. Acidophilus Can Inhibit Cephalosporin Resistant E. Coli.
TLDR
Findings suggest that bacteriocin produced by Lactobacillus fermentum and LactOBacillus acidophilus can be used for the infection control of cephalosporin resistant Escherichia coli.
Preliminary characterization of bacteriocins produced by Enterococcus faecium and Enterococcus faecalis isolated from pig faeces
A total of 92 enterococci, isolated from the faeces of minipigs subjected to an in vivo feeding trial, were screened for the production of antimicrobial substances. Bacteriocin production was
Characterization of a heat stable anti-listerial bacteriocin produced by vancomycin sensitive Enterococcus faecium isolated from idli batter
TLDR
In the present study, the bacteriocin produced by vancomycin sensitive Enterococcus faecium El and J4 isolated from idli batter samples was characterized and was found to be heat stable and had anti-listerial activity.
Pumilicin 4, A Novel Bacteriocin with Anti-MRSA and Anti-VRE Activity Produced by Newly Isolated Bacteria Bacillus pumilus Strain WAPB4
TLDR
This present study is the first report of a novel bacteriocin, pumilicin 4, produced by B. pumilus that has potential for use as an alternative antibacterial agent for the treatment of infection with MRSA and VRE.
Bac 32, a Novel Bacteriocin Widely Disseminated among Clinical Isolates of Enterococcus faecium
TLDR
A total of 636 vancomycin-resistant Enterococcus faecium (VRE) isolates that had been obtained between 1994 and 1999 were tested for bacteriocin production, indicating that there is a high incidence of Bac 32 production among VRE clinical isolates.
Phenotypic and Genotypic Characterization of Bacteriocins in Enterococcal Isolates of Different Sources
TLDR
Genes encoding bacteriocins are widely disseminated among enterocci from different origin and more studies should be done for evaluate industrial potential of bacteriOCins.
Synergistic Effect between Colistin and Bacteriocins in Controlling Gram-Negative Pathogens and Their Potential To Reduce Antibiotic Toxicity in Mammalian Epithelial Cells
TLDR
The aim of this study was to assess the in vitro activity of colistin alone or in combination with two bacteriocins, nisin A and pediocin PA-1/AcH, against Salmonella choleraesuis ATCC 14028, Pseudomonas aeruginosa ATCC 27853, Yersinia enterocolitica ATCC 9610, and Escherichia coli ATCC 35150.
Bacteriocin Production in Vancomycin-Resistant and Vancomycin-Susceptible Enterococcus Isolates of Different Origins
TLDR
The results obtained suggest that the epidemiology of vancomycin resistance may be influenced by different factors, including bacteriocin production, and that this could be a new bacteriOCin.
Partial Purification and Characterization of the Mode of Action of Enterocin S37: A Bacteriocin Produced by Enterococcus faecalis S37 Isolated from Poultry Feces
TLDR
Enterocin S37 is hydrophobic, anti-Listeria and likely acting by depletion of intracellular K+ ions upon action on KATP channels, according to the purification and characterize of this bacteriocin.
...
1
2
3
4
5
...