A novel bacterial pathogen, Microbacterium nematophilum, induces morphological change in the nematode C. elegans

@article{Hodgkin2000ANB,
  title={A novel bacterial pathogen, Microbacterium nematophilum, induces morphological change in the nematode C. elegans},
  author={Jonathan Hodgkin and Patricia E. Kuwabara and Brit Corneliussen},
  journal={Current Biology},
  year={2000},
  volume={10},
  pages={1615-1618}
}
The Dar (deformed anal region) phenotype, characterized by a distinctive swollen tail, was first detected in a variant strain of Caenorhabditis elegans which appeared spontaneously in 1986 during routine genetic crosses [1,2]. Dar isolates were initially analysed as morphological mutants, but we report here that two independent isolates carry an unusual bacterial infection different from those previously described [3], which is the cause of the Dar phenotype. The infectious agent is a new… CONTINUE READING
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Characterisation of Caenorbabditis elegans lectin-binding mutants

  • CD Link, MA Silverman, M Breeen, KE Watt, SA Dames
  • Genetics
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