A novel approach identifies new differentially methylated regions (DMRs) associated with imprinted genes.

Abstract

Imprinted genes are critical for normal human growth and neurodevelopment. They are characterized by differentially methylated regions (DMRs) of DNA that confer parent of origin-specific transcription. We developed a new strategy to identify imprinted gene-associated DMRs. Using genome-wide methylation profiling of sodium bisulfite modified DNA from normal… (More)
DOI: 10.1101/gr.111922.110

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