A novel approach: chemical relational databases, and the role of the ISSCAN database on assessing chemical carcinogenicity.

@article{Benigni2008ANA,
  title={A novel approach: chemical relational databases, and the role of the ISSCAN database on assessing chemical carcinogenicity.},
  author={Romualdo Benigni and Cecilia Bossa and Ann Marie Richard and Chihae Yang},
  journal={Annali dell'Istituto superiore di sanita},
  year={2008},
  volume={44 1},
  pages={48-56}
}
Mutagenicity and carcinogenicity databases are crucial resources for toxicologists and regulators involved in chemicals risk assessment. Until recently, existing public toxicity databases have been constructed primarily as "look-up-tables" of existing data, and most often did not contain chemical structures. Concepts and technologies originated from the structure-activity relationships science have provided powerful tools to create new types of databases, where the effective linkage of chemical… CONTINUE READING

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