A novel antioxidant flavonoid (IdB 1031) affecting molecular mechanisms of cellular activation.

@article{Ursini1994ANA,
  title={A novel antioxidant flavonoid (IdB 1031) affecting molecular mechanisms of cellular activation.},
  author={Fulvio Ursini and Matilde Maiorino and Paolo Morazzoni and Antonella Roveri and Giorgio Pifferi},
  journal={Free radical biology & medicine},
  year={1994},
  volume={16 5},
  pages={547-53}
}
In searching for new drug candidates which could help bridge the gaps between free radical oxidations, pathophysiological responses, and pharmacological treatment, a series of flavonoids was screened. The most interesting compound emerging from this screening, the flavone 3'-hydroxyfarrerol (IdB 1031), is presented in this article. This compound is a good inhibitor of microsomal lipid peroxidation induced by either iron-adenosine 5'-diphosphate (ADP) or carbon tetrachloride. The elevated rate… CONTINUE READING

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