A novel antibacterial diterpene from Premna schimperi.


A novel diterpene, (5R, 8R, 9S, 10R)-12-oxo-ent-3,13(16)-clerodien-15-oic acid, has been obtained from the leaves of Premna schimperi (Verbenaceae) using an anti-microbial bioassay-guided isolation procedure. The diterpene was identified on the basis of spectroscopic data and is active against the Gram-positive bacteria Staphylococcus aureus and Bacillus… (More)


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@article{Habtemariam1990ANA, title={A novel antibacterial diterpene from Premna schimperi.}, author={Solomon Habtemariam and Alexandra Gray and Gavin W Halbert and Peter Waterman}, journal={Planta medica}, year={1990}, volume={56 2}, pages={187-9} }