A novel and highly sensitive acetyl-cholinesterase biosensor modified with hollow gold nanospheres.

Abstract

In this work, a highly sensitive acetylcholinesterase (AChE) inhibition-based amperometric biosensor has been developed. Firstly, a glassy carbon electrode (GCE) was modified with chitosan (Chits). Then, hollow gold nanospheres (HGNs) were absorbed onto the surface of chitosan based on the strong affinity through electrostatic adsorption. After that, L… (More)
DOI: 10.1007/s00449-012-0782-5

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