A novel adipocytokine, vaspin inhibits platelet-derived growth factor-BB-induced migration of vascular smooth muscle cells.

@article{Phalitakul2012ANA,
  title={A novel adipocytokine, vaspin inhibits platelet-derived growth factor-BB-induced migration of vascular smooth muscle cells.},
  author={Sukanya Phalitakul and Muneyoshi Okada and Yukio Hara and Hideyuki Yamawaki},
  journal={Biochemical and biophysical research communications},
  year={2012},
  volume={423 4},
  pages={844-9}
}
Vaspin is a novel adipocytokine originally identified in visceral white adipose tissues of Otsuka Long-Evans Tokushima fatty rats, an animal model of type 2 diabetes. We have previously shown that vaspin has anti-inflammatory effects in vascular smooth muscle cells (SMCs). SMCs migration is an important process for development atherosclerosis. However, effects of vaspin on SMCs migration remain to be clarified. Rat mesenteric arterial SMCs were treated with platelet-derived growth factor (PDGF… CONTINUE READING