A novel activating role of SRC and STAT3 on HGF transcription in human breast cancer cells

@article{Sam2007ANA,
  title={A novel activating role of SRC and STAT3 on HGF transcription in human breast cancer cells},
  author={Michelle R Sam and Bruce E. Elliott and Christopher R. Mueller},
  journal={Molecular Cancer},
  year={2007},
  volume={6},
  pages={69 - 69}
}
We have previously determined that the HGF promoter can be transactivated by a combination of activated Src and wild-type Stat3 in the mouse breast cell lines HC11 and SP1. To determine if this pathway is of relevance for the human disease, a series of human breast and other human cells lines were examined, and the status of key proteins in these cells… CONTINUE READING