A novel X-ray powder diffractometric method for studying the reaction between pseudoephedrine enantiomers.

@article{Duddu1997ANX,
  title={A novel X-ray powder diffractometric method for studying the reaction between pseudoephedrine enantiomers.},
  author={Sarma P. Duddu and A Khin-Khin and David J. W. Grant and Raj Suryanarayanan},
  journal={Journal of pharmaceutical sciences},
  year={1997},
  volume={86 3},
  pages={340-5}
}
The opposite enantiomers of pseudoephedrine were observed to react in the solid state to form the racemic compound. A novel powder X-ray diffractometric method was developed for studying the kinetics and mechanism of this reaction. The powder X-ray diffraction patterns of the enantiomers were identical, but the racemic compound exhibited a different pattern because of its different crystal structure. The powder patterns of the enantiomers and the racemic compound revealed that the 4.62 and 4.25… CONTINUE READING