A novel SMC protein complex in Schizosaccharomyces pombe contains the Rad18 DNA repair protein.

@article{Fousteri2000ANS,
  title={A novel SMC protein complex in Schizosaccharomyces pombe contains the Rad18 DNA repair protein.},
  author={Maria I. Fousteri and A. R. Lehmann},
  journal={The EMBO journal},
  year={2000},
  volume={19 7},
  pages={1691-702}
}
In Schizosaccharomyces pombe, rad18 is an essential gene involved in the repair of DNA damage produced by ionizing radiation and in tolerance of UV-induced DNA damage. The Rad18 protein is a member of the SMC (structural maintenance of chromosomes) superfamily, and we show that, like the other SMC proteins in condensin and cohesin, Rad18 is a component of a high-molecular-weight complex. This complex contains at least six other proteins, the largest of which is Spr18, a novel SMC family member… CONTINUE READING

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