A novel SLC39A4 gene mutation in the family of an acrodermatitis enteropathica patient with an unusual presentation.

@article{Wang2008ANS,
  title={A novel SLC39A4 gene mutation in the family of an acrodermatitis enteropathica patient with an unusual presentation.},
  author={Sheng Ling Wang and Lin Yun Xue and Z-P Guo and L Wang and Yong Yang},
  journal={The British journal of dermatology},
  year={2008},
  volume={159 4},
  pages={976-8}
}
Acrodermatitis enteropathica (AE; OMIM 201100) is a rare autosomal recessive disorder that occurs due to insufficient zinc uptake by the intestine and that affects young infants usually at the time of weaning. It is manifested as periorificial and acral dermatitis, alopecia and diarrhoea, and is commonly associated with low serum zinc levels. Zinc supplementation is the main treatment strategy adopted for AE. In 2001, the AE gene was mapped to 8q24Æ3, and the SLC39A4 gene in this region has… CONTINUE READING