A novel NH(2)-terminal, nonhydrophobic motif targets a male germ cell-specific hexokinase to the endoplasmic reticulum and plasma membrane.

@article{Travis1999ANN,
  title={A novel NH(2)-terminal, nonhydrophobic motif targets a male germ cell-specific hexokinase to the endoplasmic reticulum and plasma membrane.},
  author={Alexander J Travis and D. -D. Sui and Klaus Dieter Riedel and Nancy R Hofmann and Stuart B. Moss and Janet E. Wilson and Gregory S. Kopf},
  journal={The Journal of biological chemistry},
  year={1999},
  volume={274 48},
  pages={34467-75}
}
Although three germ cell-specific transcripts of type 1 hexokinase exist in murine male germ cells, only one form, HK1-sc, is found at the protein level. This single isoform localizes to three distinct structures in mouse spermatozoa: the membranes of the head, the mitochondria in the midpiece, and the fibrous sheath in the flagellum (Travis, A. J., Foster, J. A., Rosenbaum, N. A., Visconti, P. E., Gerton, G. L., Kopf, G. S., and Moss, S. B. (1998) Mol. Biol. Cell 9, 263-276). The mechanism by… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

Mammalian sperm metabolism: oxygen and sugar, friend and foe.

The International journal of developmental biology • 2008
View 3 Excerpts

Similar Papers

Loading similar papers…