A novel NF-kappa B complex containing p65 homodimers: implications for transcriptional control at the level of subunit dimerization.

@article{Ganchi1993ANN,
  title={A novel NF-kappa B complex containing p65 homodimers: implications for transcriptional control at the level of subunit dimerization.},
  author={Parham A Ganchi and Shao-cong Sun and Warner C. Greene and Dean W. Ballard},
  journal={Molecular and cellular biology},
  year={1993},
  volume={13 12},
  pages={7826-35}
}
The predominant inducible form of the NF-kappa B transcription factor is a heteromeric complex containing two Rel-related DNA-binding subunits, termed p65 and p50. Prior transfection studies have shown that when these p65 and p50 subunits are expressed independently as stable homodimers, p65 stimulates kappa B-directed transcription, whereas p50 functions as a kappa B-specific repressor. While authentic p50 homodimers (previously termed KBF1) have been detected in nuclear extracts from… CONTINUE READING
28 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 28 extracted citations

Similar Papers

Loading similar papers…