A novel IKK inhibitor prevents progression of restenosis after arterial injury in mice.

Abstract

Restenosis after percutaneous coronary intervention (PCI) is still a clinically serious problem. We examined the treatment efficacy of IMD-0354, a novel IKK inhibitor, on arteriopathy. Using C57BL/6J mice, a wire-injury model was prepared and the mice were intraperitoneally injected with IMD-0354 or vehicle twice a day. The vehicle-treated injured arteries… (More)

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Cite this paper

@article{Hamaya2012ANI, title={A novel IKK inhibitor prevents progression of restenosis after arterial injury in mice.}, author={Rikuta Hamaya and Masahito Ogawa and Naho Kobayashi and Jun-Ichi Suzuki and Akiko Itai and Yasunobu Hirata and Ryozo Nagai and M Isobe}, journal={International heart journal}, year={2012}, volume={53 2}, pages={133-8} }