A novel HPLC method for quantification of 10 antiepileptic drugs or metabolites in serum/plasma using a monolithic column.

@article{Heideloff2010ANH,
  title={A novel HPLC method for quantification of 10 antiepileptic drugs or metabolites in serum/plasma using a monolithic column.},
  author={Courtney Heideloff and Dustin R. Bunch and Sihe Wang},
  journal={Therapeutic drug monitoring},
  year={2010},
  volume={32 1},
  pages={102-6}
}
Therapeutic drug monitoring of antiepileptic drugs (AEDs) is important in maximizing the therapeutic response while minimizing the adverse effects. High-performance liquid chromatography (HPLC) is the most commonly used technique for this purpose. Recently, commercial monolithic columns were introduced, which consist of a single rod of fused silica or polymer. The objective of this work was to develop a simple and fast method to quantify 10 commonly measured AEDs or metabolites [carbamazepine… CONTINUE READING

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Isocratic reversed-phase HPLC for simultaneous separation and determination of seven antiepileptic drugs and two of their active metabolites in human plasma

  • CL Ma, Z Jiao, Y Jie
  • Chromatographia
  • 2007

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