A novel HLA-DRβI sequence from the DRw11 haplotype

  title={A novel HLA-DR$\beta$I sequence from the DRw11 haplotype},
  author={V. Steimle and A. Hinkkanen and M. Schlesier and J. Epplen},
The most striking feature of major histocompatibility complex (MHC)-encoded molecules is their extensive variability (for a thorough review see Klein 1986). The interaction of MHC proteins with T cells during antigen presentation and recognition is crucial for the course of the immune response (Klein 1986). The heterodimeric HLA-DR molecules are the most abundantly expressed MHC class II molecules in man. Their high degree of polymorphism is entirely due to the variability of the DR~ chains… Expand
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Nomenclature for factors of the HLA system, 1989.


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  • P. Rollini, B. Mach, J. Gorski
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 1985
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