A novel HLA-DRβI sequence from the DRw11 haplotype

@article{Steimle2004ANH,
title={A novel HLA-DR$\beta$I sequence from the DRw11 haplotype},
author={V. Steimle and A. Hinkkanen and M. Schlesier and J. Epplen},
journal={Immunogenetics},
year={2004},
volume={28},
pages={208-210}
}
The most striking feature of major histocompatibility complex (MHC)-encoded molecules is their extensive variability (for a thorough review see Klein 1986). The interaction of MHC proteins with T cells during antigen presentation and recognition is crucial for the course of the immune response (Klein 1986). The heterodimeric HLA-DR molecules are the most abundantly expressed MHC class II molecules in man. Their high degree of polymorphism is entirely due to the variability of the DR~ chains… Expand
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