A novel FK506-like binding protein interacts with the glucocorticoid receptor and regulates steroid receptor signaling.

@article{McKeen2008ANF,
  title={A novel FK506-like binding protein interacts with the glucocorticoid receptor and regulates steroid receptor signaling.},
  author={Hayley D. McKeen and Kerry McAlpine and Andrea Valentine and Derek J. Quinn and Keeva McClelland and Christopher C. Byrne and Martin O'Rourke and Sheila Young and Christopher James Scott and Helen O McCarthy and David Graham Hirst and Tracy Robson},
  journal={Endocrinology},
  year={2008},
  volume={149 11},
  pages={5724-34}
}
FKBP-like (FKBPL) protein is a novel immunophilin-like protein that plays a role in the cellular stress response. Its three tetratricopeptide repeat motifs are homologous to the heat shock protein 90 interaction sites of other immunophilins that have roles in steroid hormone receptor signaling. In this study, using biomolecular complementation and… CONTINUE READING