A novel F-box protein is required for caspase activation during cellular remodeling in Drosophila.

Abstract

Terminal differentiation of male germ cells in Drosophila and mammals requires extensive cytoarchitectural remodeling, the elimination of many organelles, and a large reduction in cell volume. The associated process, termed spermatid individualization, is facilitated by the apoptotic machinery, including caspases, but does not result in cell death. From a… (More)
DOI: 10.1242/dev.050088

Topics

7 Figures and Tables

Cite this paper

@article{Bader2010ANF, title={A novel F-box protein is required for caspase activation during cellular remodeling in Drosophila.}, author={M. J. Bader and Eli Arama and Hermann Steller}, journal={Development}, year={2010}, volume={137 10}, pages={1679-88} }