A novel CXCR4 antagonist for hematopoietic stem cell mobilization.

Abstract

BACKGROUND Hematopoietic stem cell (HSC) transplantation is a treatment option for hematological malignancies. Current mobilization regimes frequently result in inadequate numbers of HSC for transplant therefore alternative methods of mobilization are required. OBJECTIVE The chemokine receptor CXCR4 and ligand SDF-1 are integrally involved in HSC homing… (More)
DOI: 10.1517/13543784.17.11.1749

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Cite this paper

@article{Fricker2008ANC, title={A novel CXCR4 antagonist for hematopoietic stem cell mobilization.}, author={Simon Paul Fricker}, journal={Expert opinion on investigational drugs}, year={2008}, volume={17 11}, pages={1749-60} }