A novel Affibody bioconjugate for dual-modality imaging of ovarian cancer.
@article{Wang2014ANA,
title={A novel Affibody bioconjugate for dual-modality imaging of ovarian cancer.},
author={Yihong Wang and Zheng Miao and Gang Ren and Yingding Xu and Zhen Cheng},
journal={Chemical communications},
year={2014},
volume={50 85},
pages={
12832-5
}
}An Affibody based dual imaging probe (PET and optical imaging) has been successfully developed. Dendrimer PAMAM G0 was used as a platform to assemble an NIRF dye, a metal chelator, and Affibody for dual modality imaging of ovarian cancer. Excellent tumor imaging quality was achieved in both modalities in the living tumor mice models.
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