A novel, single, transmembrane protein CATSPERG is associated with CATSPER1 channel protein.

@article{Wang2009ANS,
  title={A novel, single, transmembrane protein CATSPERG is associated with CATSPER1 channel protein.},
  author={Haikun Wang and Jin Yan Liu and Kwang-Hyun Cho and Dejian Ren},
  journal={Biology of reproduction},
  year={2009},
  volume={81 3},
  pages={539-44}
}
All four CATSPER channel pore-forming subunits (CATSPER1-4) are localized in the sperm principal piece. They form an alkalization-activated Ca2+-permeable channel and are required for sperm-hyperactivated motility, egg coat penetration, and male fertility. Unlike many other ion channels, the composition of the CATSPER protein complex is poorly defined. Herein, we describe the novel protein CATSPERG associated with the CATSPER complex. CATSPERG is predicted to be a single transmembrane-spanning… CONTINUE READING
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